Glossary

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Term of the Day

Informed consent

Informed consent is the process in which a health care provider educates a patient about the risks, benefits, and alternatives of a given procedure or intervention. The patient must be competent to make a voluntary decision about whether to undergo the procedure or intervention.

C

Clinician-reported outcome (ClinRO)

A clinical-reported outcome (ClinRO) is a type of clinical outcome assessment (COA). A measurement based on a report that comes from a trained health-care professional after observation of a patient’s health condition. Most ClinRO measures involve a clinical judgment or interpretation of the observable signs, behaviors, or other manifestations related to a disease or condition. ClinRO measures cannot directly assess symptoms that are known only to the patient. ClinRO measures include:

  • Reports of particular clinical findings (e.g., presence of a skin lesion or swollen lymph nodes) or clinical events (stroke, heart attack, death, hospitalization for a particular cause), which can be based on clinical observations together with biomarker data, such as electrocardiogram (ECG) and creatine phosphokinase (CPK) results supporting a myocardial infarction
  • Rating scales, such as:
        - Psoriasis Area and Severity Index (PASI) for measurement of severity and extent of a patient’s psoriasis
        - Hamilton Depression Rating Scale (HAM-D) for assessment of depression

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