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Term of the Day

Informed consent

Informed consent is the process in which a health care provider educates a patient about the risks, benefits, and alternatives of a given procedure or intervention. The patient must be competent to make a voluntary decision about whether to undergo the procedure or intervention.


Real-world evidence (RWE)

Real-World Evidence (RWE) refers to data and evidence derived from real-world clinical practice, such as data from electronic health records (EHRs), claims databases, patient registries, and other sources of healthcare data.

RWE is distinct from data collected in controlled clinical trials, which are conducted under tightly controlled conditions with a specific patient population and a pre-defined set of inclusion and exclusion criteria. In contrast, RWE reflects the real-world experiences of patients in diverse healthcare settings, and can provide insights into the safety, effectiveness, and value of treatments in routine clinical practice.RWE is increasingly being used by healthcare stakeholders, including regulators, payers, and providers, to inform decision-making related to drug development, regulatory approvals, coverage decisions, and clinical practice guidelines. RWE can also be used to identify unmet medical needs, inform clinical trial design, and support post-marketing surveillance and safety monitoring.

Overall, RWE is a valuable source of data and evidence for understanding the safety, effectiveness, and value of healthcare interventions in real-world clinical practice, and is increasingly being used to inform healthcare decision-making across the healthcare ecosystem.

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